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Episodes
The Peter Attia DriveEpisode 4071:59:22#407 ‒ Preventing cardiovascular and Alzheimer's disease: lowering LDL early, APOE4, and promising new therapies | Michael Davidson, M.D.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Michael Davidson is a world-renowned cardiologist, lipidologist, and the founding CEO of NewAmsterdam Pharma. He begins this episode by sharing how his family history s
The Human Upgrade: Biohacking for Longevity & PerformanceEpisode 15350:12:05What 36 Hours Without Sugar Does to Your Body : 1535
This episode walks through an hour-by-hour timeline of what happens in your body during 36 hours without sugar — from falling insulin and dwindling glycogen to fat burning, ketone production, autophagy, and hormonal reset — explaining how cutting sugar reverses insulin resistance and drives visible physical improvements.
Boundless Life3837 minA Memory & Learning Expert Reveals His Secrets To Training Your Brain & MASTERING Your Mind, With Jim Kwik
Full show notes: BenGreenfieldLife.com/limitlessdaily In this episode, you'll hear repeat guest Jim Kwik talk about cognitive offloading and where the line sits between using your phone as a second brain and letting your own memory go slack. We dig into the MIT study that scanned essay writers' brai
The Human Upgrade: Biohacking for Longevity & PerformanceEpisode 15340:09:48New Seafood Superfood, Apple Watch Health Age, Botanical Drugs, Cannabis IQ, and Blueberries : 1534
This week's biohacking roundup covers anti-aging plasmalogens from sea squirts, major new Apple Watch health-monitoring features (including passive hypertension detection), an FDA push to modernize botanical drug regulation, a study linking adolescent-onset cannabis dependence to cognitive decline, and a blueberry compound that may help muscle cells burn fat.
The Tim Ferriss ShowEpisode 8822:13:41#882: Why Kids Can Learn 10x Faster Than We Think — Niels Hoven of Mentava (Tim Coaching Session)
This episode is a bit different. It's a live, unscripted working session with a founder, and I've only done one other earlier this year.Niels Hoven (@NielsHoven) is the founder and CEO of Mentava, a company building software to support fast learners. Eager kids are dramatically underserved by today's education system, and Niels created Mentava to allow students to achieve their potential. Prior to Mentava, Niels worked at Cloudflare, ClassDojo, and Pocket Gems, where he ran the highest-grossing mobile game in the world in 2011. He has a graduate degree in electrical engineering from UC Berkeley.This episode is brought to you by:Fin powerful AI Agent for all your customer service: Fin.Ai/TimShopify global commerce platform, providing tools to start, grow, market, and manage a retail business: Shopify.com/TimWealthfront high-yield cash account: Wealthfront.com/TimNew clients get 3.30% base APY from program banks + additional 0.75% boost for 3 months on your uninvested cash (max $150k balance). Terms and conditions apply. The Cash Account offered by Wealthfront Brokerage LLC (“WFB”) member FINRA/SIPC, not a bank. The base APY as of 1/30/26 is representative, can change, and requires no minimum. Tim Ferriss, a non-client, receives compensation from WFB for advertising and holds a non-controlling equity interest in the corporate parent of WFB, which creates a conflict of interest. Individual experiences and outcomes will differ. Instant withdrawals may be limited by your receiving firm and other factors. Investment advisory services provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, not bank-guaranteed or FDIC-insured, and may lose value.Timestamps:[00:00:00] Start.[00:01:32] What Mentava is—and the toddlers reading before age three.[00:08:31] Game design, slot-machine motivation, and lowering the hoop.[00:11:54] Tim's red pen: rewriting the bio and positioning.[00:16:59] The real problem: wasted early years, high-school pressure.[00:23:55] Learning at your own pace—and "what if you did nothing?"[00:29:32] Dog-fish, fish-dog: readiness, failed trials, and follow-ups.[00:35:06] The $500 price, school pilots, and videos-for-tuition scholarships.[00:41:39] Teach a kid to fish: selling relief, not nagging.[00:47:49] Viral posts, the culture-war trap, and why exaggeration is death.[00:55:05] Put the ask on top: investor updates and what actually converts.[00:59:35] The thirty-year phonics war—and it's not with teachers.[01:01:10] A $1,000 coupon, zero takers: why the referral bribe flopped.[01:08:04] Lead with the love letters: testimonials, homepage, and who's buying.[01:20:03] "No scam charges $500 a month": pricing and who you're not for.[01:34:16] Uncrowded channels and workshopping like a standup.[01:42:08] Don't let Amazon be your debutante ball: testing what sells.[01:46:42] Alpha School, the competitive map, and the eager investor.[01:48:39] Reaching the already-converted: be the painkiller, TiE, surround sound.[02:08:18] Niels's charge: advocate for your child, unapologetically.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim’s email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferriss See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Boundless Life3071 minThis Guy Healed Knee Arthritis *Without* Surgery (& Chest-Pressed 555lbs For 14 Reps) - Cellular Hydration Secrets With John Jubilee
Full show notes: BenGreenfieldLife.com/jubilee In this episode, John Jubilee makes the case that almost everything you have been told about hydration is beside the point. His argument is that the water is not the problem, the cell is: that a membrane gets progressively harder to penetrate as you age
Longevity Optimization with Kayla Barnes-Lentz1:00:18Dr. Will Cole: How to Heal Your Cells, Leaky Gut, Light Exposure, and Why Your Gut Sets the Pace To Aging
We talk about aging like it happens to a whole person at once. It doesn't. It happens organ by organ, at different speeds, and most people never find out which part of them is running ahead until something breaks. Dr. Will Cole has spent sixteen years running one of the first functional medicine telehealth centers in the world, and he came to this conversation with a case that is both clinical and personal. In 2023 his father lost consciousness at the wheel and died in the crash. The autopsy pointed to cardiometabolic changes, and his heart cells had been aging faster than the rest of him. That same year, Stanford researchers found that one in five adults over fifty has at least one organ aging faster than the others, and that when it's the heart, the risk of a cardiac event more than triples. His new book with Dr. Josh Axe, Heal Your Cells, makes an argument that reframes most of what gets called normal aging. Exhaustion, brain fog, the weight that will not move, the hormone shifts nobody can explain. These are not the calendar. They are cells that have stopped reading their own instructions clearly, and that is a state you can change. We get into what actually makes a cell feel unsafe, why your gut lining is one cell thick and therefore the first thing to break, and the point almost nobody makes about elimination diets: the reintroduction matters as much as the elimination, and a protocol you never came off of is a cast you left on until the muscle atrophied. We also get into light. Not just morning sun, but the darkness half, which matters more for women than most people realize. Melatonin is not only a sleep hormone, it's one of the more important antioxidants for ovarian aging, and light levels most people would call almost nothing can cut its production substantially. Track your sleep, recovery, strain, and HRV with WHOOP. Get one month free at https://join.whoop.com/kaylabarnes Optimize your sleep with the Eight Sleep Pod. Get up to $350 off at https://www.eightsleep.com/Kayla with code “ KAYLA ” Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women. https://kayla-barnes-lentz.circle.so/female-longevity-community Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter: https://x.com/femalelongevity Website: https://www.kaylabarnes.com/ Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054 Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227 Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Connect with Dr. Will:Website: http://drwillcole.com/ Book: https://drwillcole.com/books-home-page/ Instagram: https://www.instagram.com/drwillcole LinkedIn: https://www.linkedin.com/in/drwillcole/ YouTube: https://www.youtube.com/user/DrWillCole #cellularhealth #longevity #femalelongevity #guthealth #healthspan #leakygut #womenshealth #functionalmedicine #circadianhealth #autophagy #mitochondria #healthoptimization
Huberman Lab2153 minEssentials: Genes & the Inheritance of Memories Across Generations | Dr. Oded Rechavi
In this Huberman Lab Essentials episode, my guest is Dr. Oded Rechavi, a professor at Tel Aviv University who studies genetics, epigenetics and the inheritance of acquired traits. We discuss how DNA, RNA and epigenetic mechanisms determine what information can pass between generations, and why acquired traits are generally not thought to be inherited. We also explain research in C. elegans showing how small RNAs can transmit antiviral resistance and influence behavior across generations, what these findings might mean for mammals and humans, and potential future applications for reproductive health and diagnostics. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Oded Rechavi (00:00:24) DNA, Genome, RNA & Proteins (00:03:43) Somatic vs. Germ Cells; Inheritance (00:06:05) Sponsor: Eight Sleep (00:07:23) Lamarck vs. Darwin, Inheritance of Acquired Traits (00:09:45) Weismann Barrier, Epigenetic Reprogramming (00:13:05) RNA & Transgenerational Inheritance (00:13:54) Model Organisms, C. elegans (00:16:59) Inheritance of Acquired Traits in C. elegans (00:17:14) Sponsor: AG1 (00:18:40) RNA Interference, Small RNAs & Gene Silencing (00:22:46) Viral Resistance Across Generations (00:24:53) Small RNAs, Mammals & Inherited Effects (00:26:00) Brain Activity, Memory & Heritable Information (00:28:46) Neuronal Small RNAs & Behavior Across Generations (00:29:59) Germ Cells, Development & Heritable RNA (00:31:29) Sponsor: LMNT (00:33:11) Future Applications, Exercise, IVF & RNA Diagnostics (00:35:16) Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
The Human Upgrade: Biohacking for Longevity & PerformanceEpisode 15331:09:00Everything You Need To Know About Your Poop | Gut Surgeon Explains : 1533
Dave Asprey and Dr. Karan Rajan dive deep into gut health, covering fiber science, fermentation, sodium myths, and the weirdest things a GI surgeon has ever removed from a patient.
Huberman LabEpisode 2977441 minHow Mitochondria Control Your Metabolism | Dr. Jared Rutter
Dr. Jared Rutter, PhD, Professor of Biochemistry at the University of Utah and Howard Hughes Medical Institute Investigator, is a leading expert on mitochondria and metabolism. He explains how mitochondria produce the energy for your cells to work but also how they regulate cell growth and replication and thereby contribute to health and disease. We also discuss how mitochondria are linked to aging, cancer, and other diseases. Our conversation explores your metabolism as the composite of trillions of individual cells and points to new ways to improve health, avoid, and treat diseases. Show notes: https://go.hubermanlab.com/297-jared-rutter Pre-order Protocols: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Jared Rutter (00:02:29) Metabolism, Cells; Aging (00:08:36) Mitochondria, Origin & Cell Complexity (00:13:07) Sponsors: Joovv & BetterHelp (00:15:16) Mitochondria Genome, Inheritance (00:18:18) Mitochondria & Spatial Distribution; Cell-Specific Metabolism (00:25:59) Nutrient Energy, Hormones, Fat Cells (00:31:13) Glucose, ATP Conversion, Pyruvate (00:36:41) Cell Choice: Energy or Growth, Cancer; Virus (00:46:02) Sponsors: AG1 & Eight Sleep (00:48:36) Microbiome, Role of Humans (00:51:44) Molecule Discovery Process, MPC1, MPC2 (00:59:42) Cell Resource Sensing, Fasting, Glucagon, Fat Cells; Neurons, Heart (01:07:03) Cell Resource Allocation, MPC, Heart Failure; Disease (01:11:46) Sponsor: Function (01:13:24) Cell Size vs Fuel Balance, Cell Identity & Disease (01:20:43) MPC Discovery, Genetics, Model Systems (01:24:29) Lactate, Oxygen, Exercise; Energy Prioritization Hierarchy (01:31:32) Cancer, Mutations, Metabolism Changes & Warburg Effect (01:36:18) Cancer Challenges & Therapies (01:43:00) Therapy Combinations, Unique Cancer Mutations & Metabolism (01:48:31) Technology to Visualize Metabolism; Disease, Metabolism & Scents (01:56:34) Excess Energy & Mitochondria, Reactive Oxygen Species (02:01:12) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
- The Peter Attia Drive1:16:50
Blood pressure: how to measure, manage, and treat high blood pressure (AMA #48 rebroadcast)
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter delves into the critical subject of blood pressure, which is one of the three primary causes of atherosclerosis, along wi
The Human Upgrade: Biohacking for Longevity & PerformanceEpisode 15320:10:03If I Had To Lose 50 Pounds FAST, I’d Do THIS : 1532
Dave Asprey breaks down three science-backed rules — cutting ultra-processed food, adopting adequate fasting windows, and redesigning your environment — to lower insulin resistance and break the metabolic block that's stalling your fat loss.